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PUB Acetaminophen
PUB Tricyclic
PUB Thallium
PUB Barbiturates
PUB Carbamazepine
PUB Methanol
PUB Lithium
PUB Theophylline
PUB Metformin
PUB Salycilate
PUB Phenytoin
PUB Valproic Acid
PUB Digoxin
Introduction to EXTRIP

Ghannoum M et al. (2011) "Blood purification in toxicology: nephrology's ugly duckling." Advances in chronic kidney disease. 18(3):160-6. 

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Methodology

Lavergne V et al. (2012) "The EXTRIP workgroup: guideline methodology." Clinical toxicology  50(5):403-13. 

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Toxin Guidelines

TRICYCLIC ANTIDEPRESSANTS

Yates C et al. (2014)  "Extracorporeal treatment for tricyclic antidepressant poisoning: recommendations from the EXTRIP Workgroup." Seminars in dialysis. 27(4):381-9.

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ACETAMINOPHEN

Gosselin S et al. (2014) "Extracorporeal treatment for acetaminophen poisoning: Recommendations from the EXTRIP workgroup." Clin Toxicol. 52(8):856-67. 

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BACLOFEN

Ghannoum M et al. (2021) Recommendations from the EXTRIP workgroup on extracorporeal treatment for baclofen poisoning. Kidney Int. 100(4):720-36.

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BARBITURATES

Mactier R et al. (2014) "Extracorporeal treatment for barbiturate poisoning: recommendations from the EXTRIP Workgroup". Am J Kidney Dis 64(3): 347-358.  

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BETA-ADRENERGIC ANTAGONISTS

Bouchard et al. (2021) Extracorporeal treatment for poisoning to B-adrenergic antagonists: systematic review and recommendations from the EXTRIP workgroup. Crit Care. 25(1):201. 

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CALCIUM CHANNEL BLOCKERS

Wong A et al. (2021) Extracorporeal treatment for calcium channel blocker poisoning: systematic review and recommendations from the EXTRIP workgroup. Clin Toxicol. 59(5):361-75.

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CARBAMAZEPINE

Ghannoum et al. (2014) "Extracorporeal treatment for carbamazepine poisoning: systematic review and recommendations from the EXTRIP workgroup." Clin Toxicol. 52(10): 993-1004. 

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DIGOXIN

Mowry JB et al. (2016) "Extracorporeal treatment for digoxin poisoning: systematic review and recommendations from the EXTRIP Workgroup." Clin Toxicol. 54(2):103-14  

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ETHYLENE GLYCOL

Ghannoum M et al. (2023): "Extracorporeal treatment for digoxin poisoning: systematic review and recommendations from the EXTRIP Workgroup." Crit Care.

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GABAPENTIN / PREGABALIN

Bouchard et al. (2021) "Extracorporeal treatment for digoxin poisoning: systematic review and recommendations from the EXTRIP Workgroup." AJKD. 

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ISONIAZID

Mowry JB, et al. (2021) Extracorporeal treatments for isoniazid poisoning: Systematic review and recommendations from the EXTRIP workgroup. Pharmacotherapy. 41(5):463-78.

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LITHIUM

Decker B et al. (2015) "Extracorporeal Treatment for Lithium Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup." Clin J Am Soc Nephro 10(5):875-87  

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METHANOL

Roberts DM et al. (2015)  "Recommendations for the Role of Extracorporeal Treatments in the Management of Acute Methanol Poisoning: A Systematic Review and Consensus Statement." Critical Care Medicine 43(2): 461-472.

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METHOTREXATE

Ghannoum, M., et al. (2022). "Extracorporeal Treatment for Methotrexate Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup." Clin J Am Soc Nephrol.

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METFORMIN

Calello D, et al. (2015) "Extracorporeal Treatment for Metformin Poisoning: Systematic Review and Recommendations From the EXTRIP Workgroup." Crit Care Med. 43(8):1716-30  

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PHENYTOIN

Anseeuw K et al. (2016) "Extracorporeal Treatment in Phenytoin Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup." Am J Kidney Dis. 67(2):187-97  

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QUININE / CHLOROQUINE / HYDROXYCHLOROQUINE

Berling I et al. (2020) "Extracorporeal Treatment for Chloroquine, Hydroxychloroquine, and Quinine Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup." JASN. 31(10):2475-89

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SALICYLATE

Juurlink DN et al. (2015) "Extracorporeal Treatment for Salicylate Poisoning: Systematic Review and Recommendations From the EXTRIP Workgroup." Ann Emerg Med. 266(2):165-81. 

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THALLIUM

Ghannoum M et al. (2012) "Extracorporeal treatment for thallium poisoning: recommendations from the EXTRIP Workgroup."  Clin J Am Soc Nephrol 2012 7(10): 1682-1690 

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THEOPHYLLINE

Ghannoum M et al. (2015) "Extracorporeal treatment for theophylline poisoning: Systematic review and recommendations from the EXTRIP workgroup." Clin Toxicol. 53(4): 215-229.  

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VALPROIC ACID

Ghannoum M et al. (2015) "Extracorporeal treatment for valproic acid poisoning: Systematic review and recommendations from the EXTRIP workgroup." Clin Toxicol. 53(5): 454-465.  

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Reporting Guidelines

Lavergne V et al. (2014) "Guidelines for reporting case studies on extracorporeal treatments in poisonings: methodology." Seminars in dialysis. 27(4):407-14.  

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Other Publications by EXTRIP Members

Campion GH et al. (2019). "Extracorporeal treatments in poisonings from four non-traditionally dialysed toxins (acetaminophen, digoxin, opioids and tricyclic antidepressants): A combined single-centre and national study." Basic Clin Pharmacol Toxicol 124(3): 341-347.

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Bouchard J et al. (2017). "Availability and cost of extracorporeal treatments for poisonings and other emergency indications: a worldwide survey." Nephrol Dial Transplant 32(4): 699-706.

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Cormier, MJ et al. (2017). "Phenytoin overdose treated with hemodialysis using a high cut-off dialyzer." Hemodial Int 21(1): E13-E17.

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Lavergne V et al. (2016). "Why are we Still Dialyzing Overdoses to Tricyclic Antidepressants? A subanalysis of the NPDS database." Semin Dial 29(5): 403-409.

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Ghannoum M et al. (2016). "Practice Trends in the Use of Extracorporeal Treatments for Poisoning in Four Countries." Semin Dial 29(1): 71-80.

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Ghannoum M et al. (2014). "Hemoperfusion for the treatment of poisoning: technology, determinants of poison clearance, and application in clinical practice." Semin Dial 27(4): 350-361.

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Ghannoum M et al. (2014). "A stepwise approach for the management of poisoning with extracorporeal treatments." Semin Dial 27(4): 362-370.

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Ouellet G et al. (2014). "Available extracorporeal treatments for poisoning: overview and limitations." Semin Dial 27(4): 342-349.

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Mardini J et al. (2014). "Case reports of extracorporeal treatments in poisoning: historical trends." Semin Dial 27(4): 402-406.

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Bouchard J et al. (2014). "Principles and operational parameters to optimize poison removal with extracorporeal treatments." Semin Dial 27(4): 371-380.

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Roberts DM, Gosselin S. (2014) "Variability in the management of lithium poisoning." Seminars in dialysis. 27(4):390-4. 

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Hoffman RS. (2014) "100 Years of Blood Purification in Poisoning: Closing the Gap Between Anecdotal Care And Evidence-Based Therapy. Seminars in dialysis." 27(4): 340-341

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